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GLUTEN GUARDIAN

EAT GLUTEN AND GET AWAY WITH IT!

  • Gluten Guardian is a blend of 6 plant-based proteolytic enzymes that includes Peptidase DPP-IV (an enzyme clinically proven to help break down gluten) — as well as three enzymes that break down starches and sugars
  • Gluten Guardian is specifically designed to support digestive issues relating to gut-irritating foods containing gluten or casein, found in wheat and dairy
  • Gluten Guardian contains AstraZyme, a proprietary blend of plant-based proteases and Panax ginseng and Astragalus. These extracts improve amino acid and peptide absorption at the cellular level
  • Even if you eat gluten-free, most restaurant kitchens do not separate gluten-containing foods. This means there’s always the risk of gluten exposure anytime you eat out.
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Gluten Guardian is a one of a kind gluten-digesting enzyme blend designed to optimize digestion of meals that contain gluten and dairy.

  • Supports the digestion of hard to digest gluten and dairy casein
  • Specifically designed to support digestion from high-carbohydrate meals
  • Offers relief from occasional gas, bloating, and indigestion from high-carbohydrate meals with three enzymes that break down starches and sugars
  • Improves digestion and absorption of nutrients
  • Supports muscle building with a blend of six plant-based proteolytic enzymes that are active across all acidity/alkalinity levels
  • Astrazyme boosts protein digestion and absorption at the cellular level
  • Free of fillers, artificial colors, flavors, and preservatives
  • Non-GMO, Soy-free, dairy-free
  • 100% plant-based and in vegetarian capsules
  • Trace minerals provide cofactors for the enzymes and support healthy glucose uptake into cells

Gluten Guardian Benefits

  1. Ensures Complete Digestion of Gluten and Casein

    Gluten is a family of proteins found in wheat, whereas casein is 80% of protein found in dairy. These proteins are difficult to digest because they are high in the amino acids proline and glutamine, which our digestive enzymes don’t recognize. As a result, they’re likely to remain undigested and stimulate the immune system, causing inflammation and autoimmunity.

    Gluten in particular can open the gut barrier through the zonulin pathway, exposing the content inside the gut to your immune system. In people predisposed for autoimmunity or allergies, the leaky gut from gluten may trigger or worsen the disease. Incompletely digested gluten fragments can also get absorbed into the bloodstream and have opioid-like activities.

    Most dairy in North America have A1 casein, which is a common food allergen. Incompletely digested casein fragments may have opioid-like activities, as mother nature designs milk to help babies bond with their mothers. However, beyond infancy, A1 casein is a strong gut irritant that can irritate and inflame the gut, and slow down gut movement by acting like opiates.

    Gluten and dairy can cause leaky gut, allowing the incomplete fragments to enter the bloodstream. Some people with compromised blood-brain barriers may experience the opiate effects from these foods. Not surprisingly, people with food addictions and emotional eating often turn to gluten and dairy. Studies suggest that some people with neurologic or mental health conditions may find their nervous system better balanced without gluten and dairy.

    If you are healthy or experience minor discomfort with gluten and dairy, it is important to take a gluten-digesting enzyme to ensure that they are 100% digested if you do eat them.

    If you have severe symptoms or flare-ups after eating gluten, you need to completely avoid gluten. However, a gluten-digesting enzyme may help with minor accidental exposure. Keep in mind, however, that Gluten Guardian is not approved to treat or prevent any disease.

  2. Enjoy Occasional High-Carb Refeed Meals and Treats Without the Bloat from Gluten and Dairy

    If you are on a restrictive diet or reaching a plateau with your weight loss program, a refeed meal allows you to enjoy your favorite foods and jumpstarts your metabolism. Even if you’re not dieting, you may want to enjoy your favorite treats while avoiding the harmful health effects.

    The problem is that eating a lot of carbs, sugar, and gluten can often cause digestive upsets and inflammation. Therefore, it is important to supplement with gluten-digesting and carbohydrate-digesting enzymes. Gluten Guardian is designed to ensure that your digestion is optimal and prevent digestive upset from these refeed meals or treats.

  3. Take Advantage of Your Cheat Meal for Muscle Building

    Your cheat or refeed meals are a way to spike your insulin levels to get glucose and amino acids into your muscle cells and replenish your glycogen stores. If you do the refeed right, you will experience better workout during the first few days after your refeed. Also, some people use holiday meals and social events as refeeds to maximize muscle gain, fuel their workouts, and minimize fat gain. In order to maximize muscle building and minimize inflammation, your protein digestion and absorption have to be optimal.

    Inflammation and leaky gut can contribute to leptin and insulin resistances, which may make you more likely to gain fat from these refeed meals. Gluten Guardian can help ensure optimal digestion, minimize undigested gluten and casein, and promote a balanced immune response. Also, AstraZyme can help maximize amino acid and peptide absorption.

  4. Reduces Post-Meal Fatigue and Brain Fog

    Being tired and brain-fogged after meals are signs that your gut is working hard to digest your meals, and that you are getting inflammation from your food. A meal should simply take away your hunger, not put you to sleep. Gluten Guardian helps digest the hardest to digest gluten and casein, and also provides overall digestive support. As a result, you will feel both satiated and energized after your meals.

  5. Helps With Accidental Gluten and Dairy Exposure

    People with celiac disease and gluten allergies need to completely avoid gluten. Also, many people with inflammatory symptoms, including difficulty losing weight, are likely to have gluten intolerances, so they may find it beneficial to go gluten-free. The problem is that it takes only “parts per million” of gluten to cause severe symptoms in celiacs and gluten intolerant people, so it can be a challenge to eat out or enjoy social occasions. If the kitchen handles gluten, chances are the gluten-free dishes are contaminated with some gluten.

    The Aspergillus DPP IV has been shown to digest gluten in the gut of healthy people. People who took the enzyme had no trace of gluten left in their stomach at 1 hour, compared to 3 hours with the placebo. Also, the combination of DPP IV with pepsin (a stomach protease), such as found in Gluten Guardian®, can significantly reduce more gluten peptides than either enzyme alone.

    Gluten-digesting enzymes do not give a free pass for celiacs and gluten intolerant people to eat as much gluten as they want. However, many well-controlled Celiacs find these enzymes helpful in cases of accidental gluten or dairy exposure. Some find that it provides significant relief after gluten exposure. However, Gluten Guardian is not approved to treat any conditions and individual responses may vary widely. Remember to work with your healthcare professional to decide what’s best for you.

  6. Helps With Leaky Gut and Food Sensitivities

    Leaky gut, or intestinal permeability, allows partially digested foods and bacterial toxins to reach the bloodstream and stimulate the immune system. Many people with leaky gut develop food sensitivities and allergies, with gluten and dairy being two of the most common culprits.

    Optimizing your overall digestion, and ensuring that gluten and casein are completely digested, can support gut barrier health. These may also help mitigate food sensitivities.

How Does Gluten Guardian Work?

Gluten Guardian supports digestive function, especially for high-carb meals. It contains full-spectrum protein-digesting and carbohydrate-digesting enzymes. Astrazyme in Gluten Guardian promotes a balanced immune response and maximizes amino acid absorption.

The most important enzyme in Gluten Guardian is Peptidase DPP-IV, a potent gluten-digesting enzyme. It can also digest casein, a hard to digest protein that makes up 80% of milk proteins. Therefore, Gluten Guardian helps you fully break down gluten and casein into amino acids that your body can use. By fully digesting them, the enzyme helps minimize immune responses to incompletely digested gluten and casein.

When To Take Gluten Enzymes?

Take Gluten Guardian with meals that contain gluten, dairy, or any high-carbohydrate meals.

Gluten Guardian can also be taken on an empty stomach to harness the benefits of systemic protein-digesting enzymes. These include promoting exercise recovery, breaking down inflammatory proteins and scar tissues, and wound healing.

Symptoms of Non-Celiac Gluten Sensitivity

Non-celiac gluten sensitivity (in short, “gluten sensitivity”) is a form of gluten intolerance that is milder than celiac disease. However, not all symptoms of gluten sensitivity have to do with the gut. Also, some symptoms of gluten and other food sensitivity can arise up to 72 hours after consuming the food.

Gluten sensitivity symptoms include:

  • Abdominal pain
  • Digestive upset
  • Gas and bloating
  • Symptoms of irritable bowel syndrome, such as constipation or diarrhea
  • Acid reflux
  • Fatigue
  • Brain fog
  • Skin problems
  • Mood issues
  • Psychosis
  • Unhealthy and unexplained weight loss
  • Inability to lose weight
  • Anemia
  • Autoimmune disorders
  • Aches and pains
  • Numbness
  • Cancers
  • Atopy or tendency to develop allergic diseases
Gluten Guardian® Questions:
What is the recommended dosage for Gluten Guardian®?

Take 3 capsules with water at the beginning of each meal for optimal digestion.

Do not exceed 9 capsules per day.

Consult your medical practitioner prior to starting any new supplement.

Can children take Gluten Guardian®? If so, what is the recommended dosage?

Gluten Guardian® is safe for children. The recommended dose is 1 capsule for every 50 lbs.

Consult your medical practitioner prior to starting any new supplement.

I have a clean diet, why would I need to take Gluten Guardian®?

Gluten and casein are sticky proteins that are very difficult to digest. They also tend to stimulate the immune system, which can lead to inflammatory symptoms, both inside and outside the gut. Gluten Guardian® is great for the occasions that you want to indulge in gluten-containing foods or eat out, especially if you have some sensitivity to gluten or dairy. However, it is not an approved treatment for Celiac disease, severe gluten intolerance, or allergies.

I am already taking digestive enzymes. So why do I need to take Gluten Guardian®?

Most digestive enzymes don’t contain enzymes that digest the most difficult to digest parts of gluten and casein, such as DPP-IV. Gluten Guardian® contains a high dose of DPP-IV, along with other synergistic enzymes that optimize your digestion after consuming gluten-containing meals.

DPP IV is a family of enzymes, some of which control hormones, neuronal function, and inflammation in your body. Some food substances, including but not limited to partially digested gluten and casein, may cause symptoms by inhibiting enzymes in the DPP-IV family. Some diabetic drugs increase insulin by inhibiting pancreatic DPP-IV, but also cause severe joint pain as a side effect. Therefore, some people benefit from supplementing with digestive DPP IV on a regular basis to reduce food-based DPP IV inhibitors in the gut. However, keep in mind that Gluten Guardian® is not approved to treat any disease and you should consult your physician.

How many capsules are in a Gluten Guardian® bottle?

The Gluten Guardian® bottle contains 90 capsules.

Can someone who has celiac disease take Gluten Guardian®?

Gluten Guardian® is not an approved treatment for any disease, including Celiac disease or gluten allergy. Neither is it a replacement for a gluten-free diet to manage health conditions that arise from gluten consumption. However, many well-controlled Celiacs find Gluten Guardian® to be an excellent safety net when they have foods that may have small amounts of gluten contamination. Some find that it provides significant relief after gluten exposure. However, individual responses vary widely, so you need to work with your healthcare professional to decide what’s best for you.

Is it okay for pregnant or breastfeeding mothers to take Gluten Guardian®?

Pregnant or breastfeeding mothers should consult a medical practitioner prior to starting any new supplement, diet, or training program.

Can I empty the contents of the capsule in a beverage?

The contents of the capsules can be dissolved in your beverage of choice. Doing so will not improve nor diminish absorption or the health benefits you obtain.

What is the shelf life for Gluten Guardian®?

The shelf life for Gluten Guardian® is 2 years from the manufactured date, which can be found on the bottle.

How should you store Gluten Guardian®?

Store Gluten Guardian® in a cool and dry place.

Frequently Asked Questions:
How is gluten broken down in the body?

Gluten is a group of proteins found in wheat. Like other proteins, it gets digested by protein-digesting enzymes called proteases. Each protease typically recognizes a certain amino acid pattern. However, gluten has an odd structure consisting of a lot of glutamine and proline, which makes it difficult for any protease other than DPP-IV to digest.

How do I become gluten free?

Becoming gluten-free involves cutting out bread, pasta, regular oats, and all foods that contain gluten. Gluten is found in wheat, rye, and barley. It can also come hidden in sauces, salad dressing, marinade, alcoholic drinks, or as thickeners. You will need to learn to read food labels to identify components that may contain gluten. Celiacs and people who are very sensitive have to make sure that all of their foods are made in gluten-free facilities and have never touched gluten, because even parts per million of gluten can provoke symptoms. We recommend working with a certified gluten-free practitioner.

If gluten has been causing you inflammation, you’ll likely experience less bloating, lowered inflammation, clearer skin, more energy, and less brain fog. However, keep in mind that a gluten-free diet is not for everyone or a cure-all. You should check with your healthcare practitioner to address your health issues.

What is celiac disease?

Celiac disease is an autoimmune condition found in genetically predisposed people. When people with Celiac disease consume gluten, their immune system attacks the gut lining. This typically results in severe digestive symptoms and nutritional deficiencies due to malabsorption. People with Celiac disease are at a higher risk of developing other autoimmune disease, both due to their genetics, inflammation, and leaky gut. Also, many people with obscure inflammatory symptoms or other autoimmune disease have undiagnosed Celiac disease. The only way to manage Celiac disease is to strictly avoid gluten. Celiacs can become very sick if their foods have touched a gluten-containing food or cooked in a container that used to have gluten.

Gluten Guardian® is not a replacement for strict gluten avoidance to manage Celiac disease. However, many Celiacs find that Gluten Guardian® helps them with occasional low-dose gluten exposure, such as when they eat out. It also helps them feel safer to have Gluten Guardian® as a safety net. Even so, individual responses may vary, so you should consult with your physician.

Although Gluten Guardian® can potently break down the immunogenic parts of gluten, it may not fully keep gluten from the gut lining. Therefore, we do not advise that Celiacs use Gluten Guardian® to liberally eat bread or pasta.

What are the symptoms of celiac disease?

Celiac disease is associated with the following conditions, although they’re not always caused by Celiac disease or gluten. Therefore, if you have these conditions that don’t respond to any other treatments, speak to your doctor about a possible Celiac diagnosis.

  • Fatigue
  • Constipation, Diarrhea, or alternating
  • Bloating and gas
  • Nausea and vomiting
  • Weight loss or inability to lose weight
  • Brain fog
  • Headache
  • Inability to focus or ADHD
  • Hormone imbalances
  • Infertility and miscarriage
  • Skin problems
  • Joint pain
  • Other autoimmune conditions

Symptoms of severe nutrient deficiency may also be caused by Celiac disease:

  • Iron deficiency anemia
  • Loss of bone density
  • Mouth ulcers
  • Tingling of hands and feet

A Celiac diagnosis may require blood tests for antibodies against gluten, genetic tests for HLA-DQ2 and HLA-DQ8 genes, and colonoscopy. Visible damages to the small intestine lining on colonoscopy would confirm Celiac disease.

Non-Celiac Gluten Sensitivity (also called Gluten Sensitivity or Intolerance) refers to any other inflammatory symptoms caused by gluten consumption that are not caused by autoimmunity. It is a less-defined and less recognized condition than Celiac disease.

If you are gluten-sensitive rather than Celiac, you may not have antibodies against gluten or visible damages in your gut lining through endoscopy. However, you will experience significant relief of some inflammatory symptoms when you go gluten-free, and the symptoms will return once you start to eat gluten again.

Gluten allergy is one of the most common food allergies that can be diagnosed with the presence of IgE antibodies in the blood. Like other food allergies, it can result in acute and severe allergic symptoms such as runny nose, hives, asthma, headache, stomachache, vomiting, diarrhea, or anaphylaxis.

In all of these cases, the best way to manage it is to strictly and completely avoid gluten.

What foods trigger celiac disease?

There are 3 components that trigger Celiac disease:

  • Genetic predispositions, such as the HLA-DQ2 and HLA-DQ8 genes, and family history of autoimmunity.
  • A life event that triggers autoimmunity, such as infections, stress or trauma, pregnancy, or surgery
  • Gluten consumption

Gluten-containing foods may include (may not be exhaustive list):

  • Wheat
  • Rye
  • Barley
  • Einkorn
  • Spelt
  • Semolina
  • Beer
  • Malt
  • Brewer’s yeast
  • Wheat starch
  • Farro
  • Graham
  • Kamut
  • Bread and all baked goods
  • Pasta
  • Breakfast cereals
  • Pancakes, waffles, crepes, and biscuits
  • Croutons
  • Flour tortillas
  • Soy sauce
  • Salad dressing and marinade*
  • Soup*
  • Starch
  • Grain alcohol*

*Depending on the ingredient. Best to choose the certified gluten-free option.

What is casein?

Casein is a protein that comprises 82% majority of milk protein. Like gluten, it is very difficult to digest with normal digestive enzymes due to its structure. Cow’s milk in North America tends to be A1 milk, with digestion resistant fragments that can act like opiates (casomorphins). A1 casomorphins can provoke inflammation, causing digestive problems and inflammatory health conditions. Therefore, A1 milk can cause milk intolerance that is not caused by lactose intolerance. There is no medical test that can diagnose casein intolerance other than elimination-challenge.

Casein allergy is a food allergy that can be diagnosed with the skin prick test or blood test for IgE antibodies against milk. People with milk allergy will experience allergic symptoms such as hives, asthma, or anaphylaxis.

The DPP-IV enzyme in Gluten Guardian® can help completely break down the casein in your diet, thus reducing its immunogenicity. Other enzymes in Gluten Guardian® also help ensure optimal digestion for occasional indulgence. However, Gluten Guardian® is not approved to treat dairy intolerance or allergies.

If you develop skin problems, bloating, or any inflammatory symptoms with dairy consumption, you should avoid dairy and casein. If you struggle to get enough proteins for your fitness goals, consider taking MassZymes with every meal to maximize your protein absorption.

What is proteolytic enzyme?

Proteolytic (proteo = protein, lytic = break) enzymes or proteases digest proteins into peptides and eventually into amino acids. Pepsin is secreted in the stomach, whereas most other proteases are produced by the pancreas and secreted in the small intestine. These enzymes are important because incompletely digested proteins means less amino acids available for your body. It also means that some of these protein fragments could contribute to food allergies or other food-related inflammation. Incompletely digested proteins and unabsorbed amino acids will further get fermented by the gut bacteria. The protein and amino acid fermentation process tend to create unhealthy byproducts, so it is best to ensure that most of the protein you eat is available to you rather than your gut bacteria.

Proteolytic enzymes are also important for wound healing, resolution of inflammation, and exercise recovery. When consumed with foods, proteolytic enzymes help digest food in the gut. However, when consumed on an empty stomach, plant proteolytic enzymes, such as those in AstraZyme, can be absorbed into the bloodstream. These plant enzymes can also support your natural healing processes from injuries, inflammation, or exercise training.

What is amylase and its function?

Amylases are enzymes that digest starch into maltose and subsequently glucose. Glucose is the sugar that can be absorbed and used as fuel every cell in your body.

What does amylase help our bodies do?

If you have some ongoing imbalances in your gut bacteria or don’t usually eat a lot of carbs, a high-carb meal can cause bloating due to inflammation and bacterial fermentation. Gluten Guardian® contains three different types of amylase, which function at a full-spectrum of pH, to ensure that all the carbs get broken down into glucose.

What is protease?

Proteolytic (proteo = protein, lytic = break) enzymes or proteases digest proteins into peptides and eventually into amino acids. Pepsin is secreted in the stomach, whereas most other proteases are produced by the pancreas and secreted in the small intestine. These enzymes are important because incompletely digested proteins means less amino acids available for your body. It also means that some of these protein fragments could contribute to food allergies or other food-related inflammation. Incompletely digested proteins and unabsorbed amino acids will further get fermented by the gut bacteria. The protein and amino acid fermentation process tend to create unhealthy byproducts, so it is best to ensure that most of the protein you eat is available to you rather than your gut bacteria.

Proteolytic enzymes are also important for wound healing, resolution of inflammation, and exercise recovery. When consumed with foods, proteolytic enzymes help digest food in the gut. However, when consumed on an empty stomach, plant proteolytic enzymes, such as those in AstraZyme, can be absorbed into the bloodstream. These plant enzymes can also support your natural healing processes from injuries, inflammation, or exercise training.

What is protease used for?

Proteases are important to dissolve blood clots (they thin the blood also), and plant proteases help dissolve blood clots or adhesions that result from initial wound closures. Plant proteases in supplemental form do not help with cell division, unfolded protein responses, or autophagy.

Why are protease enzymes important?

The acid-alkalinity of the blood is very narrowly regulated. Any more than 0.1 change in pH can result in near-death sickness or death. The acid/alkalinity that's discussed in health is actually the acid/alkalinity of the urine. However, the theory that either one is healthy has been debunked. There is no scientific basis behind alkalinity of the blood leading to anxiety or insomnia.

What is lipase?

Lipase is an enzyme that helps break down fat into glycerol and three fatty acid molecules.

What is DPP IV?

DPP IV or DPP 4 stands for prolyl dipeptidyl peptidase IV. It is a family of enzymes that cut behind proline and alanine. Proline is an odd amino acid that has a rigid ring structure and introduces a kink into the protein, making it impossible for most proteases to digest proteins that contain a lot of proline. The DPP IV group of enzymes is present throughout the human body, helping to activate some peptide hormones, other enzymes, inflammatory substances, and neurotransmitters.

Some drugs, and incompletely digested peptides of gluten and casein can overwhelm and block the natural DPP IV enzymes that participate in these other biological processes. For example, Substance P is a 10 amino acid neuropeptide that controls pain sensation and anxiety, and is deactivated by a DPP IV. For sensitive people, consuming dairy and gluten on a regular basis can block DPP IV and increase substance P, leading to increased pain.

People who suffer from elevated substance P may benefit from supplementing with a high-dose digestive DPP IV on a regular basis to reduce any food substance that may inhibit their own natural DPP IV. However, Gluten Guardian® is not approved to treat any disease and you should consult your physician, especially if you are taking medications.

Where is DPP 4 Produced?

The DPP IV in Gluten Guardian® comes from a fungus Aspergillus, which is used in oriental cultures to ferment soybeans.

The Aspergillus DPP IV has been shown to digest gluten in the gut of healthy people. People who took the enzyme had no trace of gluten left in their stomach at 1 hour, compared to 3 hours with the placebo. Also, the combination of DPP IV with pepsin (a stomach protease), such as found in Gluten Guardian®, can significantly reduce more gluten peptides than either enzyme alone.

The other DPP IV family enzymes found in your body are present on the surface of the linings of the gut and kidneys, blood vessels, liver and pancreas, glandular cells, and white blood cells.

Can taking digestive enzymes be harmful?

Digestive enzymes exist within your body and digestive enzyme supplements are generally safe. However, you should avoid digestive enzymes if you have gastritis or ulcer in your digestive system. Also, digestive enzymes may interact with diabetes medications and blood thinners, so you should always consult your doctors if you are on any medications.

Are supplements to digest gluten safe and useful?

Peptidase DPP IV is generally safe. Also, a randomized clinical trial demonstrated that the gluten-digesting enzyme can significantly digest most gluten in the stomach before the food reaches the small intestine. While gluten-digesting enzymes are not treatments for Celiac disease, it helps with digesting gluten and casein in the gut.

Why is gluten so bad for you?

There are many reasons why gluten is bad for you. Plants can’t run away, so they create proteins that are toxic to animals who eat them. Gluten is one such protein that always stimulates your immune system and opens your gut barrier.

People who are optimally healthy have the immune systems that can ignore the wheat component and control disease-causing inflammation. However, suboptimal conditions, such as having high stress, unhealthy gut, dysbiosis, unhealthy diets, low enzymes, and poor sleep will allow gluten to become a problem.

Gluten Guardian | Eat Gluten And Get Away With It
  • Made in USA
  • FDA Approved
  • NSF Certified
  • GMP Certified
  • Manufacturing COA

Product Information

Product Dimensions:

  • Cap diameter: 1.5 inches
  • Bottom diameter: 2 inches
  • Height: 4 inches
  • Weight: 2.2 ounces

Caution:

Do not use if ulcer or gastritis are present.

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Gluten Guardian Reviews

Scientific Studies
  1. Balakireva AV, Zamyatnin AA. Properties of Gluten Intolerance: Gluten Structure, Evolution, Pathogenicity and Detoxification Capabilities. Nutrients. 2016;8(10):644. Published 2016 Oct 18. doi:10.3390/nu8100644
  2. Brooke-Taylor S, Dwyer K, Woodford K, Kost N. Systematic Review of the Gastrointestinal Effects of A1 Compared with A2 β-Casein. Adv Nutr. 2017;8(5):739-748. Published 2017 Sep 15. doi:10.3945/an.116.013953
  3. Fasano A. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. F1000Res. 2020;9:F1000 Faculty Rev-69. Published 2020 Jan 31. doi:10.12688/f1000research.20510.1
  4. Pruimboom L, de Punder K. The opioid effects of gluten exorphins: asymptomatic celiac disease. J Health Popul Nutr. 2015;33:24. Published 2015 Nov 24. doi:10.1186/s41043-015-0032-y
  5. Shewry PR, Hey SJ. Do we need to worry about eating wheat?. Nutr Bull. 2016;41(1):6-13. doi:10.1111/nbu.12186
  6. Mkumbuzi L, Mfengu MMO, Engwa GA, Sewani-Rusike CR. Insulin Resistance is Associated with Gut Permeability Without the Direct Influence of Obesity in Young Adults. Diabetes Metab Syndr Obes. 2020;13:2997-3008. Published 2020 Aug 24. doi:10.2147/DMSO.S256864
  7. Jeanrenaud B, Rohner-Jeanrenaud F. Effects of neuropeptides and leptin on nutrient partitioning: dysregulations in obesity. Annu Rev Med. 2001;52:339-351. doi:10.1146/annurev.med.52.1.339
  8. Salden BN, Monserrat V, Troost FJ, et al. Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Aliment Pharmacol Ther. 2015;42(3):273-285. doi:10.1111/apt.13266
  9. Ehren J, Morón B, Martin E, Bethune MT, Gray GM, Khosla C. A food-grade enzyme preparation with modest gluten detoxification properties. PLoS One. 2009;4(7):e6313. Published 2009 Jul 21. doi:10.1371/journal.pone.0006313
  10. Fasano A. Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications. Clin Gastroenterol Hepatol. 2012;10(10):1096-1100. doi:10.1016/j.cgh.2012.08.012
  11. Salden BN, Monserrat V, Troost FJ, et al. Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Aliment Pharmacol Ther. 2015;42(3):273-285. doi:10.1111/apt.13266
  12. Lauret E, Rodrigo L. Celiac disease and autoimmune-associated conditions. Biomed Res Int. 2013;2013:127589. doi:10.1155/2013/127589
  13. Celiac disease - Diagnosis and treatment - Mayo Clinic. Mayoclinic.org. Accessed February 23, 2021.
  14. Lundin KE. Non-celiac gluten sensitivity - why worry?. BMC Med. 2014;12:86. Published 2014 May 23. doi:10.1186/1741-7015-12-86
  15. Brooke-Taylor S, Dwyer K, Woodford K, Kost N. Systematic Review of the Gastrointestinal Effects of A1 Compared with A2 β-Casein. Adv Nutr. 2017;8(5):739-748. Published 2017 Sep 15. doi:10.3945/an.116.013953
  16. Pal S, Woodford K, Kukuljan S, Ho S. Milk Intolerance, Beta-Casein and Lactose. Nutrients. 2015;7(9):7285-7297. Published 2015 Aug 31. doi:10.3390/nu7095339
  17. Nongonierma AB, FitzGerald RJ. Susceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis. Food Chem. 2014;145:845-852. doi:10.1016/j.foodchem.2013.08.097
  18. Oliphant K, Allen-Vercoe E. Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health. Microbiome. 2019;7(1):91. Published 2019 Jun 13. doi:10.1186/s40168-019-0704-8
  19. Busek P, Stremenová J, Krepela E, Sedo A. odulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines. Physiol Res. 2008;57(3):443-449.
  20. Salden BN, Monserrat V, Troost FJ, et al. Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Aliment Pharmacol Ther. 2015;42(3):273-285. doi:10.1111/apt.13266
  21. Ehren J, Morón B, Martin E, Bethune MT, Gray GM, Khosla C. A food-grade enzyme preparation with modest gluten detoxification properties. PLoS One. 2009;4(7):e6313. Published 2009 Jul 21. doi:10.1371/journal.pone.0006313
  22. Deacon CF. Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes [published correction appears in Front Endocrinol (Lausanne). 2019 May 03;10:275]. Front Endocrinol (Lausanne). 2019;10:80. Published 2019 Feb 15. doi:10.3389/fendo.2019.00080
  23. König J, Holster S, Bruins MJ, Brummer RJ. Randomized clinical trial: Effective gluten degradation by Aspergillus niger-derived enzyme in a complex meal setting. Sci Rep. 2017;7(1):13100. Published 2017 Oct 12. doi:10.1038/s41598-017-13587-7

EAT GLUTEN AND GET AWAY WITH IT!

  • Gluten Guardian is a blend of 6 plant-based proteolytic enzymes that includes Peptidase DPP-IV (an enzyme clinically proven to help break down gluten) — as well as three enzymes that break down starches and sugars
  • Gluten Guardian is specifically designed to support digestive issues relating to gut-irritating foods containing gluten or casein, found in wheat and dairy
  • Gluten Guardian contains AstraZyme, a proprietary blend of plant-based proteases and Panax ginseng and Astragalus. These extracts improve amino acid and peptide absorption at the cellular level
  • Even if you eat gluten-free, most restaurant kitchens do not separate gluten-containing foods. This means there’s always the risk of gluten exposure anytime you eat out.